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Enzymes

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"Enzymes: A Very Short Introduction explores enzymes, the tiny molecular machines that make life possible. These proteins speed up chemical reactions inside a living organism many millionfold. Working together, teams of enzymes carry out all the processes that can be collectively recognized as life, from making DNA to digesting food. This VSI explains how this catalysis works, before going on to reveal how these catalysts of such extraordinary power and exquisite selectivity have evolved. It also examines the many varied ways in which individual enzymes are used nowadays as tools - in medical diagnosis and therapy, washing powders, food production, waste treatment, and chemical synthesis. New vistas have opened up through application of molecular genetics, not only allowing cheap, large-scale production of pure enzymes but also making possible new, tailor-made enzymes"--

Enzymes

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DNA methylation, a modification found in most species, regulates chromatin functions in conjunction with other epigenome modifications, such as histone post-translational modifications and non-coding RNAs. In mammals, DNA methylation has an essential role in development by orchestrating the generation and maintenance of the phenotypic diversity of human cell types. Recent years have brought spectacular advances in our understanding of the mechanism, function and regulation of DNA methyltransferases through their interaction with other epigenome modifications, chromatin factors and post-translational modifications, which are described in this Special Issue of Genes. Manuscripts are specifically addressing describing the targeting and regulation of DNA methyltransferases by interacting factors and their roles in cellular differentiation and the development of diseases. Prof. Dr. Albert Jeltsch and Prof. Dr. Humaira Gowher, Guest Editors.

Enzymes

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ENZYMES

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Enzymes